CD38 / Brilliant Ultraviolet 496 / HIT2
CD38 / Brilliant Ultraviolet 496 / HIT2
Citations:
(2)
Product Details
Supplier | BD Biosciences | |
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Catalog #: | 564658 (View supplier product page) | |
Size | 25 Tests | |
Price | ||
Antigen | CD38 | |
Clone | HIT2 | |
Host | Mouse | |
Isotype | IgG1 κ | |
Conjugate | Brilliant Ultraviolet 496 | |
Target Species | Human | |
Applications | FC | |
Description | Hu CD38 BUV496 HIT2 25Tst |
About CD38 and Brilliant Ultraviolet 496
CD38 | The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] | |
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Brilliant Ultraviolet 496 | Brilliant™ UltraViolet 496 (BUV496) is a blue-emitting tandem fluorophore that combines BD Horizon® BUV395 and an acceptor dye. It can be excited by the 355 nm UV laser and collected using a 515/30 bandpass filter. BUV496 has an excitation peak at 348 nm and an emission peak at 496 nm This dye is part of the Brilliant™ UltraViolet dye family, developed and sold by BD Biosciences. This family of dyes uses BUV395 as the donor so that all dyes in the family can be excited by the 355 nm UV laser. Depending on the acceptor, the dyes in this family have different relative brightness ratings. |