Vitronectin / DyLight 405 / 19

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-90648V (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen Vitronectin
Clone 19
Host Rabbit
Isotype IgG
Conjugate DyLight 405
Target Species Mouse
Applications ELISA, IHC, IHC-P
Description Rabbit Vitronectin antibody [DyLight 405] detects Mouse
About Vitronectin and DyLight 405
Vitronectin The protein encoded by this gene functions in part as an adhesive glycoprotein. Differential expression of this protein can promote either cell adhesion or migration as it links cells to the extracellular matrix through a variety of ligands. These ligands include integrins, plasminogen activator inhibitor-1, and urokinase plasminogen activator receptor. This secreted protein can be present in the plasma as a monomer or dimer and forms a multimer in the extracellular matrix of several tissues. This protein also inhibits the membrane-damaging effect of the terminal cytolytic complement pathway and binds to several serpin serine protease inhibitors. This protein can also promote extracellular matrix degradation and thus plays a role in tumorigenesis. It is involved in a variety of other biological processes such as the regulation of the coagulation pathway, wound healing, and tissue remodeling. The heparin-binding domain of this protein give it anti-microbial properties. It is also a lipid binding protein that forms a principal component of high density lipoprotein. [provided by RefSeq, Aug 2020]
DyLight 405 DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 405 Excitation and Emission Spectra