IL-21 R / PE-CF594 / 17A12

Product Details
Supplier BD Biosciences
Catalog #: 564122 (View supplier product page)
Size 100 Tests
Price $388.00
Antigen IL-21 R
Clone 17A12
Host Mouse
Isotype IgG1 κ
Conjugate PE-CF594
Target Species Human
Applications FC
Description Hu IL-21R (CD360) PE-CF594 17A12 100Tst
About IL-21 R and PE-CF594
IL-21 R The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]
PE-CF594 PE-CF®594 from BD Biosciences has an excitation peak at 496 nm and an emission peak at 612 nm. It is an alternative to PE-Dazzle 594, PE-Alexa 610, PE-eFluor™ 610 and PE-CF®594.
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PE-CF594 Excitation and Emission Spectra