FluoroFinder

	Supplier	BD Biosciences
	Catalog #:	564659 (View supplier product page)
	Size	50 Tests
	Price
	Antigen	CCR6
	Clone	11A9
	Host	Mouse
	Isotype	IgG1 κ
	Conjugate	Brilliant Ultraviolet 496
	Target Species	Baboon, Cynomolgus macaque, Human, Rhesus macaque
	Applications	FC
	Description	Hu CD196 (CCR6) BUV496 11A9 50Tst

	CCR6	This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
	Brilliant Ultraviolet 496	Brilliant™ UltraViolet 496 (BUV496) is a blue-emitting tandem fluorophore that combines BD Horizon® BUV395 and an acceptor dye. It can be excited by the 355 nm UV laser and collected using a 515/30 bandpass filter. BUV496 has an excitation peak at 348 nm and an emission peak at 496 nm This dye is part of the Brilliant™ UltraViolet dye family, developed and sold by BD Biosciences. This family of dyes uses BUV395 as the donor so that all dyes in the family can be excited by the 355 nm UV laser. Depending on the acceptor, the dyes in this family have different relative brightness ratings.

	Additional Sources

CCR6 / Brilliant Ultraviolet 496 / 11A9