CD8a / Brilliant Blue 515 / 53-6.7

Citations: (18)
Product Details
Supplier BD Biosciences
Catalog #: 564422 (View supplier product page)
Size 100 μg
Price $120.00
Antigen CD8a
Clone 53-6.7
Host Rat
Isotype IgG2a κ
Conjugate Brilliant Blue 515
Target Species Mouse
Applications FC
Description Ms CD8a BB515 53-6.7 100ug
About CD8a and Brilliant Blue 515
CD8a The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020]
Brilliant Blue 515 Horizon Brilliant™ Blue 515 (BB515), exclusive to BD Biosciences, is a brighter alternative to FITC and Alexa Fluor™ 488 in flow cytometry. It has an excitation peak at 590 nm and an emission peak at 515 nm.
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Brilliant Blue 515 Excitation and Emission Spectra