CD11b / Brilliant Blue 515 / M1/70

Citations: (37)
Product Details
Supplier BD Biosciences
Catalog #: 564454 (View supplier product page)
Size 100 μg
Price $172.00
Antigen CD11b
Clone M1/70
Host Rat
Isotype IgG2b κ
Conjugate Brilliant Blue 515
Target Species Human, Mouse
Applications FC
Description CD11b BB515 M1/70 100ug
About CD11b and Brilliant Blue 515
CD11b This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Brilliant Blue 515 Horizon Brilliant™ Blue 515 (BB515), exclusive to BD Biosciences, is a brighter alternative to FITC and Alexa Fluor™ 488 in flow cytometry. It has an excitation peak at 590 nm and an emission peak at 515 nm.
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Brilliant Blue 515 Excitation and Emission Spectra