IL-12 R beta 2 / DyLight 755 / 93

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-90421IR (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen IL-12 R beta 2
Clone 93
Host Rabbit
Isotype IgG
Conjugate DyLight 755
Target Species Mouse
Applications ELISA
Description Rabbit IL-12 R beta 2 antibody [DyLight 755] detects Mouse
About IL-12 R beta 2 and DyLight 755
IL-12 R beta 2 The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. Several transcript variants encoding different isoforms and non-protein coding transcripts have been found for this gene. [provided by RefSeq, Apr 2012]
DyLight 755 DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.
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DyLight 755 Excitation and Emission Spectra