IL-18 / Janelia Fluor 646 / 167

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-90394JF646 (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen IL-18
Clone 167
Host Rabbit
Isotype IgG
Conjugate Janelia Fluor 646
Target Species Mouse
Applications ELISA
Description Rabbit IL-18/IL-1F4 antibody [Janelia Fluor 646] detects Mouse
About IL-18 and Janelia Fluor 646
IL-18 The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable of stimulating interferon gamma production, and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs, and in potentially fatal conditions characterized by a cytokine storm. In humans, IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2020]
Janelia Fluor 646 Janelia Fluor® 646 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 646 has an excitation peak at 646 nm and an emission peak at 664 nm.
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Janelia Fluor 646 Excitation and Emission Spectra