CD11b / DyLight 594 / ITGAM/271

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-54563DL594 (View supplier product page)
Size 0.1 ml
Price $519.00
Antigen CD11b
Clone ITGAM/271
Host Mouse
Isotype IgG1 κ
Conjugate DyLight 594
Target Species Human
Applications FC, ICC/IF
Description Mouse CD11b antibody [DyLight 594] detects Human
About CD11b and DyLight 594
CD11b This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
DyLight 594 DyLight™ 594 has an excitation peak at 593 nm and an emission peak at 618 nm and is spectrally similar to Alexa Fluor™ 594 and Texas Red. DyLight™ 594 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 594 Excitation and Emission Spectra