CD11b / Alexa Fluor 350 / ITGAM/271

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-54563AF350 (View supplier product page)
Size 0.1 ml
Price $519.00
Antigen CD11b
Clone ITGAM/271
Host Mouse
Isotype IgG1 κ
Conjugate Alexa Fluor 350
Target Species Human
Applications FC, ICC/IF
Description Mouse CD11b antibody [Alexa Fluor 350] detects Human
About CD11b and Alexa Fluor 350
CD11b This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Alexa Fluor 350 Alexa Fluor™ 350 (AF350, Alexa 350) has an excitation peak at 346 nm and an emission peak at 442 nm, and is spectrally similar in size, brightness and application to AMCA, DyLight™ 350 and CF®350. Alexa 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 350 Excitation and Emission Spectra