AMH / Alexa Fluor 405 / 16

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-90332AF405 (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen AMH
Clone 16
Host Rabbit
Isotype IgG
Conjugate Alexa Fluor 405
Target Species Human
Applications ELISA
Description Rabbit MIS/AMH antibody [Alexa Fluor 405] detects Human
About AMH and Alexa Fluor 405
AMH This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Mutations in this gene result in persistent Mullerian duct syndrome. [provided by RefSeq, Jul 2016]
Alexa Fluor 405 Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 405 Excitation and Emission Spectra