CD59 / Alexa Fluor 700 / 14

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-90912AF700 (View supplier product page)
Size 0.1 ml
Price $518.00
Antigen CD59
Clone 14
Host Rabbit
Isotype IgG
Conjugate Alexa Fluor 700
Target Species Rat
Applications FC
Description Rabbit CD59 antibody [Alexa Fluor 700] detects Rat
About CD59 and Alexa Fluor 700
CD59 This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
Alexa Fluor 700 Alexa Fluor™ 700 (AF700, Alexa 700) has an excitation peak at 702 nm and an emission peak at 723 nm, and is spectrally similar to iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 700 is commonly used in Flow Cytometry and is similar in size, brightness and application to iFluor® 700 and Vio® R720.
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Alexa Fluor 700 Excitation and Emission Spectra