Desmocollin-2 / Alexa Fluor 488 / 3

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-90904AF488 (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen Desmocollin-2
Clone 3
Host Rabbit
Isotype IgG
Conjugate Alexa Fluor 488
Target Species Rat
Applications IHC, IHC-P
Description Rabbit Desmocollin-2 antibody [Alexa Fluor 488] detects Rat
About Desmocollin-2 and Alexa Fluor 488
Desmocollin-2 This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
Alexa Fluor 488 Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A.
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Alexa Fluor 488 Excitation and Emission Spectra