Glypican 3 / Alexa Fluor 647 / 12

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-90758AF647 (View supplier product page)
Size 100 μl
Price $449.00
Antigen Glypican 3
Clone 12
Host Rabbit
Isotype IgG
Conjugate Alexa Fluor 647
Target Species Mouse
Applications ELISA
Description Rabbit Glypican 3 antibody [Alexa Fluor 647] detects Mouse
About Glypican 3 and Alexa Fluor 647
Glypican 3 Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
Alexa Fluor 647 Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye.
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Alexa Fluor 647 Excitation and Emission Spectra