CD38 / Biotin / HIT2

Product Details
Supplier SouthernBiotech
Catalog #: 9612-08 (View supplier product page)
Size 100 Tests
Price $240.00
Antigen CD38
Clone HIT2
Host Mouse
Isotype IgG1
Conjugate Biotin
Target Species Human
Applications FC, WB, ELISA, IHC-P, IHC-Fr
Description Mouse Anti-Human CD38-BIOT
About CD38 and Biotin
CD38 The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
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Biotin Excitation and Emission Spectra