MBD3 / Alexa Fluor 488 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-00136AF488 (View supplier product page)
Size 0.1 ml
Price $369.00
Antigen MBD3
Clone
Host Rabbit
Isotype IgG
Conjugate Alexa Fluor 488
Target Species Human
Applications WB, ELISA
Description Rabbit MBD3 antibody [Alexa Fluor 488] detects Human
About MBD3 and Alexa Fluor 488
MBD3 DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. This gene belongs to a family of nuclear proteins which are characterized by the presence of a methyl-CpG binding domain (MBD). The encoded protein is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. Unlike the other family members, the encoded protein is not capable of binding to methylated DNA. The protein mediates the association of metastasis-associated protein 2 with the core histone deacetylase complex. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
Alexa Fluor 488 Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A.
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Alexa Fluor 488 Excitation and Emission Spectra