CD160 / DyLight 594 / 275
CD160 / DyLight 594 / 275
Product Details
Supplier | Novus Biologicals, a Bio-Techne brand | |
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Catalog #: | NBP2-90074DL594 (View supplier product page) | |
Size | 0.1 ml | |
Price | $549.00 | |
Antigen | CD160 | |
Clone | 275 | |
Host | Rabbit | |
Isotype | IgG | |
Conjugate | DyLight 594 | |
Target Species | Human | |
Applications | FC | |
Description | Rabbit CD160 antibody [DyLight 594] detects Human |
About CD160 and DyLight 594
CD160 | CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules. [provided by RefSeq, Jul 2008] | |
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DyLight 594 | DyLight™ 594 has an excitation peak at 593 nm and an emission peak at 618 nm and is spectrally similar to Alexa Fluor™ 594 and Texas Red. DyLight™ 594 is most commonly used in flow cytometery and fluorescence microscopy applications. |
Citations
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DyLight 594 Excitation and Emission Spectra
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