PCNA / Alexa Fluor 488 / 144

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-90058AF488 (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen PCNA
Clone 144
Host Rabbit
Isotype IgG
Conjugate Alexa Fluor 488
Target Species Human
Applications IHC, IHC-P
Description Rabbit PCNA antibody [Alexa Fluor 488] detects Human
About PCNA and Alexa Fluor 488
PCNA The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]
Alexa Fluor 488 Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A.
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Alexa Fluor 488 Excitation and Emission Spectra