CD85a / DyLight 488 / 123

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-90035G (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen CD85a
Clone 123
Host Rabbit
Isotype IgG
Conjugate DyLight 488
Target Species Human
Applications ELISA
Description Rabbit ILT5/CD85a/LILRB3 antibody [DyLight 488] detects Human
About CD85a and DyLight 488
CD85a This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
DyLight 488 DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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DyLight 488 Excitation and Emission Spectra