GFR alpha-2 / Alexa Fluor 488 / 104

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-89420AF488 (View supplier product page)
Size 0.1 ml
Price $518.00
Antigen GFR alpha-2
Clone 104
Host Rabbit
Isotype IgG
Conjugate Alexa Fluor 488
Target Species Human
Applications WB
Description Rabbit GFR alpha-2/GDNF R alpha-2 antibody [Alexa Fluor 488] reacts with Human
About GFR alpha-2 and Alexa Fluor 488
GFR alpha-2 Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Alexa Fluor 488 Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A.
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Alexa Fluor 488 Excitation and Emission Spectra