BRD2 / Biotin / MHC

Citations: (1)
Product Details
Supplier Thermo Fisher Scientific
Catalog #: 730115 (View supplier product page)
Size 100 μg
Price $299.00
Antigen BRD2
Clone MHC
Host Mouse
Isotype IgG1
Conjugate Biotin
Target Species Human
Applications IP
Description BRD2 Monoclonal Antibody, Biotin conjugate. BRD2 is a mitogen-activated kinase which localizes to the nucleus. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3 but sequence comparison suggests that the protein is not involved in the immune response. Homology to the Drosophila gene female sterile homeotic suggests that this human protein may be part of a signal transduction pathway involved in growth control.IP 0.5 mg/ml
About BRD2 and Biotin
BRD2 This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010]
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

Biotin Excitation and Emission Spectra