FERMT3 / Alexa Fluor 488 / OTI3C7

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-72241AF488 (View supplier product page)
Size 0.1 ml
Price $679.00
Antigen FERMT3
Clone OTI3C7
Host Mouse
Isotype IgG1
Conjugate Alexa Fluor 488
Target Species Human
Applications WB, IHC
Description Mouse FERMT3/URP2 antibody [Alexa Fluor 488] reacts with Human
About FERMT3 and Alexa Fluor 488
FERMT3 Kindlins are a small family of proteins that mediate protein-protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2010]
Alexa Fluor 488 Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A.
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Alexa Fluor 488 Excitation and Emission Spectra