CX3CL1 / DyLight 488 / 409

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-89590G (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen CX3CL1
Clone 409
Host Rabbit
Isotype IgG
Conjugate DyLight 488
Target Species Human
Applications ELISA, IHC, IHC-P
Description Rabbit CX3CL1/Fractalkine antibody [DyLight 488] reacts with Human
About CX3CL1 and DyLight 488
CX3CL1 This gene belongs to the CX3C subgroup of chemokines, characterized by the number of amino acids located between the conserved cysteine residues. This is the only member of the CX3C subgroup, which contains three amino acids between cysteine residues, resulting in a Cys-X-X-X-Cys configuration. The encoded protein contains an extended mucin-like stalk with a chemokine domain on top, and exists in both a membrane-anchored form where it acts as a binding molecule, or, in soluble form, as a chemotactic cytokine. The mature form of this protein can be cleaved at the cell surface, yielding different soluble forms that can interact with the G-protein coupled receptor, C-X3-C motif chemokine receptor 1 gene product. This gene plays a role in a wide range of diseases, including cancer, vasculitis, neuropathies, atherosclerosis, inflammatory diseases, and in human immunodeficiency virus infections. [provided by RefSeq, Sep 2017]
DyLight 488 DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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DyLight 488 Excitation and Emission Spectra