FluoroFinder

	Supplier	Thermo Fisher Scientific
	Catalog #:	A14929 (View supplier product page)
	Size	25 μg
	Price	$95.00
	Antigen	CD274
	Clone	10F.9G2
	Host	Rat
	Isotype	IgG2b κ
	Conjugate	APC
	Target Species	Mouse
	Applications	FC
	Description	PD-L1 / CD274 Monoclonal Antibody, APC conjugate (10F.9G2). Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a recently described B7 family member. To date, one specific receptor has been identified that can be ligated by PD-L1. This receptor, programmed death receptor 1 (PD-1), has been shown to negatively regulate T-cell receptor (TCR) signaling. Upon ligating its receptor, PD-L1 has been reported to decrease TCR-mediated proliferation and cytokine production. PD-L1 expression was found to be abundant on many murine and human cancers and could be further up-regulated upon IFN-gamma stimulation. Thus, PD-L1 might play an important role in tumor immune evasion.FACS Assay Dependent -

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CD274 / APC / 10F.9G2