Mannose 6 Phosphate Receptor / PE / MEM-238

Product Details
Supplier Thermo Fisher Scientific
Catalog #: A15775 (View supplier product page)
Size 100 Tests
Price $221.00
Antigen Mannose 6 Phosphate Receptor
Clone MEM-238
Host Mouse
Isotype IgG1
Conjugate PE
Target Species Human, Non-Human Primate
Applications FC
Description IGF2R Monoclonal Antibody (MEM-238), PE
About Mannose 6 Phosphate Receptor and PE
Mannose 6 Phosphate Receptor This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611). [provided by RefSeq, Nov 2015]
PE Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
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PE Excitation and Emission Spectra