MAPK1 / DyLight 405 / 7

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-89215V (View supplier product page)
Size 0.1 ml
Price $518.00
Antigen MAPK1
Clone 7
Host Rabbit
Isotype IgG
Conjugate DyLight 405
Target Species Human
Applications FC, ELISA, ICC/IF
Description Rabbit ERK2 antibody reacts with Human [DyLight 405]
About MAPK1 and DyLight 405
MAPK1 This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jan 2014]
DyLight 405 DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 405 Excitation and Emission Spectra