CD62L / Pacific Blue / MEL-14

Product Details
Supplier Thermo Fisher Scientific
Catalog #: RM4328 (View supplier product page)
Size 1 ml
Price $289.00
Antigen CD62L
Clone MEL-14
Host Rat
Isotype IgG2a κ
Conjugate Pacific Blue
Target Species Mouse
Applications FC
Description CD62L Monoclonal Antibody (MEL-14), Pacific Blue
About CD62L and Pacific Blue
CD62L This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]
Pacific Blue Pacific Blue® (Pac Blue, PacBlue) is a blue-emitting organic fluorophore that can be excited by the 405 nm Violet laser and captured with a 450/50 nm bandpass filter. Pacific Blue has an excititaion peak at 401 nm and an emission peak at 452 nm.
Images
  CD62L Pacific Blue Thermo Fisher Scientific antibody anti target:Mouse host:Rat isotype:IgG2a κ clone:MEL-14 C57BL/6 mouse spleen cells stained with Pacific Blue™-conjugated CD62L (Product # RM4328) and gat...

C57BL/6 mouse spleen cells stained with Pacific Blue™-conjugated CD62L (Product # RM4328) and gated on cells positive for mouse CD3 (Product # HM3401) cells (black line). The gray line represents spleen cells with isotype control.

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Pacific Blue Excitation and Emission Spectra