CD31 / Janelia Fluor 549 / C31.3 + C31.7 + C31.10

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-47785JF549 (View supplier product page)
Size 0.1 ml
Price $539.00
Antigen CD31
Clone C31.3 + C31.7 + C31.10
Host Mouse
Isotype IgG
Conjugate Janelia Fluor 549
Target Species Cynomolgus macaque, Human, Rabbit, Rat
Applications FC, IHC, IHC-P, IF
Description CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.
About CD31 and Janelia Fluor 549
CD31 The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. [provided by RefSeq, May 2010]
Janelia Fluor 549 Janelia Fluor® 549 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 549 has an excitation peak at 549 nm and an emission peak at 571 nm.
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Reviews & Ratings
Janelia Fluor 549 Excitation and Emission Spectra