CD16 / Alexa Fluor 350 / 3G8

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-81102AF350 (View supplier product page)
Size 0.1 ml
Price $485.00
Antigen CD16
Clone 3G8
Host Rabbit
Isotype IgG κ
Conjugate Alexa Fluor 350
Target Species Baboon, Chimpanzee, Cynomolgus macaque, Human, Rhesus macaque
Applications FC, IHC
Description 3G8 binds to CD16 at an epitope which is not the IgG-binding site. This antibody cannot distinguish between CD16a transmembrane isoform found on the surface of NK cells and macrophages (which can trigger the cytolytic response), and the GPI-linked CD16b isoform present on neutrophils or soluble CD16 found in the plasma. CD16 is the low affinity IgG receptor III and binds to aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis and ADCC (antibody-dependent cell-mediated cytotoxicity).
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Alexa Fluor 350 Excitation and Emission Spectra