CD80 / DyLight 350 / IDEC-114 (Galiximab)

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-81099UV (View supplier product page)
Size 0.1 ml
Price $519.00
Antigen CD80
Clone IDEC-114 (Galiximab)
Host Human
Isotype IgG1 λ
Conjugate DyLight 350
Target Species Human
Applications WB, FC, ELISA, IHC
Description Galiximab is a primatized mAb which consists of human constant and primate (cynomolgus macaque) variable regions and binds specifically to B7-1/CD80. B7-1/CD80 is a surface glycoprotein and a member of the B7 family of costimulatory molecules. B7-1/CD80 antigen regulates T cell activation (through interacting with CD28 or CD152) and is expressed transiently in antigen-presenting cells, T cells and normal B cells, and expressed consitutively on various subtypes of B-cell lymphomas.
About CD80 and DyLight 350
CD80 The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011]
DyLight 350 DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 350 Excitation and Emission Spectra