CD80 / Alexa Fluor 405 / IDEC-114 (Galiximab)

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-81099AF405 (View supplier product page)
Size 0.1 ml
Price $519.00
Antigen CD80
Clone IDEC-114 (Galiximab)
Host Human
Isotype IgG1 λ
Conjugate Alexa Fluor 405
Target Species Human
Applications WB, FC, ELISA, IHC
Description Galiximab is a primatized mAb which consists of human constant and primate (cynomolgus macaque) variable regions and binds specifically to B7-1/CD80. B7-1/CD80 is a surface glycoprotein and a member of the B7 family of costimulatory molecules. B7-1/CD80 antigen regulates T cell activation (through interacting with CD28 or CD152) and is expressed transiently in antigen-presenting cells, T cells and normal B cells, and expressed consitutively on various subtypes of B-cell lymphomas.
About CD80 and Alexa Fluor 405
CD80 The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011]
Alexa Fluor 405 Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 405 Excitation and Emission Spectra