CD357 / Biotin / YGITR765

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-81090B (View supplier product page)
Size 0.1 ml
Price $519.00
Antigen CD357
Clone YGITR765
Host Rabbit
Isotype IgG κ
Conjugate Biotin
Target Species Mouse
Applications FC
Description This antibody binds murine GITR/TNFRSF18.
About CD357 and Biotin
CD357 This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]
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Biotin Excitation and Emission Spectra