CD62L / DyLight 350 / DREG-56

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-81084UV (View supplier product page)
Size 0.1 ml
Price $519.00
Antigen CD62L
Clone DREG-56
Host Rabbit
Isotype IgG κ
Conjugate DyLight 350
Target Species Bovine, Chimpanzee, Human
Applications WB, FC
Description This antibody is specific for human L-Selectin/CD62L, a homing receptor selectively expressed on lymphocytes, which allows their entry into secondary lymphoid tissues via high endothelial venules.
About CD62L and DyLight 350
CD62L This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]
DyLight 350 DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 350 Excitation and Emission Spectra