SNAP25 / Alexa Fluor 405 / SP12

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-81057AF405 (View supplier product page)
Size 0.1 ml
Price $519.00
Antigen SNAP25
Clone SP12
Host Rabbit
Isotype IgG κ
Conjugate Alexa Fluor 405
Target Species Bovine, Feline, Guinea Pig, Hamster, Human, Mouse, Porcine, Rat
Applications WB, ELISA, IHC, ICC/IF
Description This antibody binds to native and denatured SNAP25.
About SNAP25 and Alexa Fluor 405
SNAP25 Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Alexa Fluor 405 Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 405 Excitation and Emission Spectra