IL-18 / DyLight 350 / 125-2H

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-81040UV (View supplier product page)
Size 0.1 ml
Price $519.00
Antigen IL-18
Clone 125-2H
Host Rabbit
Isotype IgG κ
Conjugate DyLight 350
Target Species Human
Applications ELISA, ICC/IF
Description Recognizes the active form of human IL-18/IL-1F4.
About IL-18 and DyLight 350
IL-18 The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable of stimulating interferon gamma production, and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs, and in potentially fatal conditions characterized by a cytokine storm. In humans, IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2020]
DyLight 350 DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 350 Excitation and Emission Spectra