RANTES / Unconjugated / VL1
RANTES / Unconjugated / VL1
Citations:
(2)
Product Details
| Supplier | BioLegend | |
|---|---|---|
| Catalog #: | 515502 (View supplier product page) | |
| Size | 100 μg | |
| Price | $153.00 | |
| Antigen | RANTES | |
| Clone | VL1 | |
| Host | Mouse | |
| Isotype | IgG2b κ | |
| Conjugate | Unconjugated | |
| Target Species | Human | |
| Applications | WB, ELISA, IHC | |
| Description | Purified anti-human RANTES (CCL5) |
About RANTES and Purified
| RANTES | This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013] |
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Images
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Western blot analysis of 50 ng recombinant human CCL5 (RANTES, carrier-free) (lane 1) and recombinant mouse CCL5 (RANTES, carrier-free) (lane 2) using anti-RANTES (CCL5) (clone VL1) antibody followed by HRP goat anti-mouse IgG (minimal x-reactivity) secondary antibody. |
Citations
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Reviews & Ratings
Purified Excitation and Emission Spectra
$153.00
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