NLRC3 / Unconjugated / Eowyn-1

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-80084 (View supplier product page)
Size 100 ug
Price $569.00
Antigen NLRC3
Clone Eowyn-1
Host Mouse
Isotype IgG1
Conjugate Unconjugated
Target Species Mouse
Applications WB
Description Detects overexpressed mouse NLRC3. Doest not detect human NLRC3. Although NLRC3 (mouse), mAb (Eowyn-1) is strong and specific (see figure), the endogenous protein has not been detected yet with this antibody (using NLRC3 KO versus WT immune cells). NLRC3 protein is probably expressed at very low levels or its translation/ stability is triggered by stimuli still to be discovered.
About NLRC3 and Purified
NLRC3 This gene encodes a NOD-like receptor family member. The encoded protein is a cytosolic regulator of innate immunity. This protein directly interacts with stimulator of interferon genes (STING), to prevent its proper trafficking, resulting in disruption of STING-dependent activation of the innate immune response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
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Purified Excitation and Emission Spectra