CD263 / Unconjugated / DJR3

Product Details
Supplier BioLegend
Catalog #: 307002 (View supplier product page)
Size 100 μg
Price $175.00
Antigen CD263
Clone DJR3
Host Mouse
Isotype IgG1 κ
Conjugate Unconjugated
Target Species Human
Applications
About CD263 and Purified
CD263 The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008]
Citations
Additional
Sources
Reviews & Ratings
Purified Excitation and Emission Spectra