CD63 / Alexa Fluor 532 / LAMP3/2788

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-78813AF532 (View supplier product page)
Size 0.1 ml
Price $529.00
Antigen CD63
Clone LAMP3/2788
Host Mouse
Isotype IgG2b κ
Conjugate Alexa Fluor 532
Target Species Human, Mouse
Applications WB, IHC, IHC-P
Description This CD63 MAb (LAMP3/2788) recognizes protein of 26kDa-60kDa, which is identified as CD63.
About CD63 and Alexa Fluor 532
CD63 The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]
Alexa Fluor 532 Alexa Fluor™ 532 (AF532, Alexa 532) has an excitation peak at 532 nm and an emission peak at 554 nm, and is spectrally similar to Cy®3 (GE Healthcare), TRITC, iFluor® 514 (ATT Bioquest) and iFluor® 546 (ATT Bioquest). Many flow cytometers are equipped with 532nm lasers, so while Alexa 532 can be used for flow cytometry, PE is more commonly used due to its brightness and spectral characteristics. This dye is commonly used for fluorescence microscopy applications.
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Alexa Fluor 532 Excitation and Emission Spectra