CD134 Monoclonal / Fluorescein / 443318

Product Details
Supplier R&D Systems
Catalog #: FAB3388F (View supplier product page)
Size 100 Tests
Price $289.00
Antigen CD134
Clone 443318
Host Rat
Isotype IgG2a
Conjugate Fluorescein
Target Species Human
Applications FC
Description Human OX40/TNFRSF4 Fluorescein-conjugated Antibody
About CD134 and Fluorescein
CD134 The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008]
Fluorescein Fluorescein is an organic fluorophore first synthesized by Aldolf Bayer in 1871. FITC, an amine-reactive derivative, is also a commonly used name for this dye. It has an excitation peak at 494 nm and an emission peak at 512 nm.
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Fluorescein Excitation and Emission Spectra