DDB2 / Unconjugated / 1F11

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: H00001643-M01 (View supplier product page)
Size 0.1 mg
Price $519.00
Antigen DDB2
Clone 1F11
Host Mouse
Isotype IgG2b κ
Conjugate Unconjugated
Target Species Human
Applications WB, ELISA
Description Reacts with damage-specific DNA binding protein 2, 48kDa.
About DDB2 and Purified
DDB2 This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
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Purified Excitation and Emission Spectra