PSMB10 / Unconjugated / 3F8

Citations: (1)
Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: H00005699-M01 (View supplier product page)
Size 0.1 mg
Price $519.00
Antigen PSMB10
Clone 3F8
Host Mouse
Isotype IgG1 κ
Conjugate Unconjugated
Target Species Human
Applications WB, ELISA, IHC, ICC/IF
Description PSMB10 - proteasome (prosome, macropain) subunit, beta type, 10 (3F8)
About PSMB10 and Purified
PSMB10 The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome. [provided by RefSeq, Jul 2008]
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Purified Excitation and Emission Spectra