BMP-15 / Unconjugated / 582703

Product Details
Supplier R&D Systems
Catalog #: MAB5917 (View supplier product page)
Size 100 μg
Price $409.00
Antigen BMP-15
Clone 582703
Host Rat
Isotype IgG2a
Conjugate Unconjugated
Target Species Mouse
Applications IHC
Description Mouse BMP-15/GDF-9B Antibody
About BMP-15 and Purified
BMP-15 This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate subunits of a disulfide-linked homodimer, or alternatively, a heterodimer, with the related protein, growth differentiation factor 9 (GDF9). This protein plays a role in oocyte maturation and follicular development, through activation of granulosa cells. Defects in this gene are the cause of ovarian dysgenesis and are associated with premature ovarian failure. [provided by RefSeq, Aug 2016]
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Purified Excitation and Emission Spectra