MMP-14 / Alexa Fluor 700 / 128527

Product Details
Supplier R&D Systems
Catalog #: FAB9181N-100UG (View supplier product page)
Size 100 μg
Price $389.00
Antigen MMP-14
Clone 128527
Host Mouse
Isotype IgG2b
Conjugate Alexa Fluor 700
Target Species Human
Applications FC
Description Human MMP-14/MT1-MMP Alexa Fluor® 700-conjugated Antibody
About MMP-14 and Alexa Fluor 700
MMP-14 Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provided by RefSeq, Jul 2008]
Alexa Fluor 700 Alexa Fluor™ 700 (AF700, Alexa 700) has an excitation peak at 702 nm and an emission peak at 723 nm, and is spectrally similar to iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 700 is commonly used in Flow Cytometry and is similar in size, brightness and application to iFluor® 700 and Vio® R720.
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Alexa Fluor 700 Excitation and Emission Spectra