GFR alpha-2 / Alexa Fluor 647 / 71515

Product Details
Supplier R&D Systems
Catalog #: FAB6131R-100UG (View supplier product page)
Size 100 μg
Price $388.00
Antigen GFR alpha-2
Clone 71515
Host Mouse
Isotype IgG1
Conjugate Alexa Fluor 647
Target Species Human
Applications FC
Description Human GFR alpha-2/GDNF R alpha-2 Alexa Fluor 647-conjugated Antibody
About GFR alpha-2 and Alexa Fluor 647
GFR alpha-2 Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Alexa Fluor 647 Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye.
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Alexa Fluor 647 Excitation and Emission Spectra