Fibroblast Activation Protein alpha / Alexa Fluor 488 / 427819

Product Details
Supplier R&D Systems
Catalog #: FAB3715G-100 (View supplier product page)
Size 100 Tests
Price $429.00
Antigen Fibroblast Activation Protein alpha
Clone 427819
Host Mouse
Isotype IgG1
Conjugate Alexa Fluor 488
Target Species Human
Applications FC
Description Human Fibroblast Activation Protein alpha /FAP Alexa Fluor® 488-conjugated Antibody
About Fibroblast Activation Protein alpha and Alexa Fluor 488
Fibroblast Activation Protein alpha The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
Alexa Fluor 488 Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A.
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Alexa Fluor 488 Excitation and Emission Spectra