GRAIL / Unconjugated /

Product Details
Supplier R&D Systems
Catalog #: AF6234-SP (View supplier product page)
Size 25 μg
Price $149.00
Antigen GRAIL
Clone
Host Sheep
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications WB
Description Human GRAIL/RNF128 Antibody
About GRAIL and Purified
GRAIL The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
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Purified Excitation and Emission Spectra