PD-1 / Alexa Fluor 700 / 996221

Product Details
Supplier R&D Systems
Catalog #: FAB77381N-100UG (View supplier product page)
Size 100 μg
Price $429.00
Antigen PD-1
Clone 996221
Host Rat
Isotype IgG2a
Conjugate Alexa Fluor 700
Target Species Mouse
Applications FC
Description Mouse PD-1 Alexa Fluor® 700-conjugated Antibody
About PD-1 and Alexa Fluor 700
PD-1 Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020]
Alexa Fluor 700 Alexa Fluor™ 700 (AF700, Alexa 700) has an excitation peak at 702 nm and an emission peak at 723 nm, and is spectrally similar to iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 700 is commonly used in Flow Cytometry and is similar in size, brightness and application to iFluor® 700 and Vio® R720.
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Alexa Fluor 700 Excitation and Emission Spectra