CD44 / Alexa Fluor 647 / C44Mab-5

Product Details
Supplier BioLegend
Catalog #: 397511 (View supplier product page)
Size 25T
Price $101.00
Antigen CD44
Clone C44Mab-5
Host Mouse
Isotype IgG1 κ
Conjugate Alexa Fluor 647
Target Species Human
Applications FC, IHC-P
Description Alexa Fluor 647 anti-human CD44
About CD44 and Alexa Fluor 647
CD44 The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]
Alexa Fluor 647 Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye.
Citations
Additional
Sources
Reviews & Ratings
Alexa Fluor 647 Excitation and Emission Spectra