Helios / PE-Cy7 / D8W4X

Product Details
Supplier Cell Signaling Technology
Catalog #: 45259S (View supplier product page)
Size 100 μl
Price $450.00
Antigen Helios
Clone D8W4X
Host Rabbit
Isotype IgG
Conjugate PE-Cy7
Target Species Human, Mouse
Applications FC
Description Helios (D8W4X) XP Rabbit mAb (PE-Cy7 Conjugate) recognizes endogenous levels of total Helios protein.
About Helios and PE-Cy7
Helios This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This protein forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
PE-Cy7 PE-Cyanine®7 (PE-Cy7, RPE-Cy7) is a far red-emitting tandem fluorophore that combines phycoerythrin (PE) and Cy7. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Cy7, which emits light that can be captured with a 780/60 nm bandpass filter. PE-CY7 has an excitation peak at 565 nm and an emission peak at 778 nm, and is a suitable alternative to PE-Vio®770 (Miltenyi) and cFluor BYG781 (Cytek).
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PE-Cy7 Excitation and Emission Spectra